Fotonica background6/28/2023 Finally, I will show an application of Bayesian filtering enabling ultra-sensitive characterization of fiber lasers and frequency combs, with potential applications in fiber sensing and quantum communication. I will discuss our proposed framework for the design and optimization of Raman amplifiers, Erbium-doped fiber amplifiers (EDFAs), and hybrid Raman+EDFA amplifiers. In this talk, I will review our recent efforts on applying ML for signal equalization in intensity-modulated directly-detected (IM/DD) systems as well as constellation shaping for long-haul coherent transmission. These strengths of ML make it applicable from the characterization of photonic devices to the optical subsystem design and full end-to-end system optimization. The machine learning (ML) toolbox provides an effective and necessary set of tools to enable such technological advancements, as ML excels at: 1) learning complex input-output mappings allowing for simple system optimization, 2) extracting optimal decision rules for highly nonlinear classification problems 3) performing ultra-sensitive signal detection, 4) solving inverse system design problems. the backbone of our communication infrastructure need to continuously evolve. PDT delivered immediately after resection as an add-on therapy of this primary brain cancer is safe and may help to decrease the recurrence risk by targeting residual tumor cells in the resection cavity.Īdvancing photonic systems through machine learningĪs our current society is highly dependent on our ability to share information, optical communication systems, i.e. At the time of the interim analysis, the actuarial 12-months progression-free survival (PFS) rate was 60% (median 17.1 months), and the actuarial 12-months OS rate was 80% (median 23.1 months). There were no unacceptable or unexpected toxicities or serious adverse effects. Follow-up included clinical examinations and brain MR imaging was performed every 3 months until tumor progression and/or death. Postoperatively, patients underwent adjuvant therapy (Stupp protocol). The standardized therapeutic approach included maximal resection (near total or gross total tumor resection (GTR)) guided by 5-ALA fluorescence-guided surgery (followed by intraoperative PDT. Ten patients with newly diagnosed GBM were enrolled and treated between May 2017 and June 2018. Thus, overall survival (OS) is quite limited and local failure remains the fundamental problem.Ī safety and feasibility trial after treating GBM intraoperatively by photodynamic therapy (PDT) after 5-aminolevulinic acid (5-ALA) administration and maximal resection was performed at The Lille University Hospital, France. The unfavorable prognosis despite maximal therapy relates to high propensity for recurrence. Glioblastoma (GBM) is the most aggressive malignant primary brain tumor. Intraoperative 5‑ALA photodynamic therapy for newly diagnosed glioblastoma patients: a preliminary analysis of the INDYGO clinical trial (NCT03048240) For the promotion of the area, the National Council for Scientific and Technological Development (CNPq), in partnership with the MCTI, launched the Public Call 01/2021 whose objective is to finance up to 11 laboratories in Photonics. Sisfóton-MCTI is a set of laboratories or networks of multi-user laboratories, of open access to public and private users, and directed to research, development and the provision of technological services, entrepreneurship and innovation in Photonics. IBFóton is the main strategic program to encourage Photonics in the Brazil with a focus on promoting innovation in Brazilian industry and scientific, technological, economic and social development and (ii) the Brazilian Photonics Laboratories System (Sisfóton-MCTI) that was established by the Ministerial Ordinance nº 4,530/2021. In addition, MCTI has been working with structuring Public Policies in Photonics, such as: (i) The Brazilian Photonics Initiative (IBFóton) that was established by the Ministerial Ordinance no. 10,137/2019, an Advisory Committee of Photonics (CCFOTO), designed to formulate, and evaluate proposals related to photonics. In order to assist the MCTI in technical discussions, the MCTI implemented, through the Presidential Ordinance no. The General Coordination of Enabling Technologies (CGTH-DETAP-SEMPI-MCTI) is the technical area responsible for carrying out Programs in the fields of Photonics. Inside the Ministry, the Secretariat of Entrepreneurship and Innovation (SEMPI-MCTI) has been responsible for Public Policies in Photonics since 2017. This presentation aims to present the Photonics initiatives carried out within the scope of the Ministry of Science, Technology and Innovation – MCTI. Initiatives of Ministry of Science, Technology and Innovation (MCTI) in Photonics
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